ea0028oc2.4 | Reproduction and bone | SFEBES2012
Vohra Shiv
, McArthur Simon
, Solito Egle
, Gillies Glenda
We have previously demonstrated that in experimental Parkinsons disease local production of oestrogens protects against striatal dopamine loss in vivo (Gillies GE. et al. Pharmacol Biochem Behav. 2004;78:51322). As neurodegenerative disease is invariably accompanied by neuroinflammation, much interest has focused on oestrogen receptor (ER)-dependent suppression of inflammatory activation of microglia, the primary innate immune cell-type in the brain, ...